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Fluorometholone ( INN, BAN, JAN) (brand names Efflumidex, Flucon, FML Forte, FML, others), also known as 6α-methyl-9α-fluoro-11β,17α-dihydroxypregna-1,4-diene-3,20-dione, is a synthetic glucocorticoid which is used in the treatment of inflammatory eye diseases [2] [3] [4] The C17α acetate ester, fluorometholone acetate (brand name Flarex en wikipedia org wiki Fluorometholone--- drugs com compare fmlTable 3 Comparison of mean spherical equivalent (SE) and its change with baseline values in each group and between groups Mean baseline IOP was 13 7 ± 2 2 mmHg and 13 7 ± 2 0 mmHg in the loteprednol and fluorometholone groups, respectively ( P > 0 05) At the first two months after operation, no significant change in IOP was seen; however Loteprednol and Fluorometholone were associated with the most and least increase in IOP, respectively The highest pressures were detected 4 weeks after surgery in the Betamethasone and Loteprednol groups and 6 weeks after surgery in the Fluorometholone group Fluorometholone was the safest among the three examined steroid drops in terms of IOP Fluorometholone (9a-fluoro-11b,17a-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione; FML) is a corticosteroid used for its glucocorticoid activity This drug is formulated in the form of an ophthalmic solution for the treatment of allergic conjunctivitis and vernal keratoconjunctivitis 24 In particular, FML is an effective antiinflammatory drug widely used to control eye inflammation 25Fluorometholone Fluorometholone is an ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye --- ncbi nlm nih gov pmc articles PMC4705914--- mayoclinic org drugs-supplements drg-20060781No lower-cost generic available Ratings & Reviews Fluorometholone ophthalmic has an average rating of 6 3 out of 10 from a total of 10 ratings on Drugs com 44% of reviewers reported a positive effect, while 22% reported a negative effect Opcon-A has an average rating of 5 6 out of 10 from a total of 35 ratings on Drugs com 47% of reviewers modernod com articles topical-options-for-treating-ocular-inflammationFluorometholone is used to treat eye conditions caused by inflammation (swelling) This medicine is a corticosteroid (steroid medicine) that helps reduce the swelling in the eye This medicine is available only with your doctor's prescription This product is available in the following dosage forms: Suspension Before Using Difluprednate ophthalmic emulsion 0 05% (Durezol, Alcon) is indicated for the treatment of inflammation and pain associated with ocular surgery It is the most potent topical steroid in our arsenal It has been shown to have double the potency of prednisolone acetate 7 Dexamethasone works on the immune system to help reduce swelling and Fluorometholone ophthalmic has an average rating of 6 3 out of 10 from a total of 10 ratings on Drugs com 44% of reviewers reported a positive effect, while 22% reported a negative effect Lumify has an average rating of 3 2 out of 10 from a total of 171 ratings on Drugs com 19% of reviewers reported a positive effect, while 74% reported a negative effect --- reviewofoptometry com article howand-whyto-choose-dry-eye-drugs--- ncbi nlm nih gov pmc articles PMC6033780--- drugs com compare fluorometholone-ophthalmicgo drugbank com drugs DB00324--- ncbi nlm nih gov pmc articles PMC5340049Outside of loteprednol, many alternative options for the treatment of ocular surface inflammation exist, including FML (fluorometholone ophthalmic suspension 0 25%, 0 1%, Allergan) or prednisolone acetate 0 12% These are available in generic formulations and can be effective in DED management, especially as they cost less than branded
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